Secretory signal peptide modification for optimized antibody-fragment expression-secretion in Leishmania tarentolae
نویسندگان
چکیده
منابع مشابه
Secretory signal peptide modification for optimized antibody-fragment expression-secretion in Leishmania tarentolae
BACKGROUND Secretory signal peptides (SPs) are well-known sequence motifs targeting proteins for translocation across the endoplasmic reticulum membrane. After passing through the secretory pathway, most proteins are secreted to the environment. Here, we describe the modification of an expression vector containing the SP from secreted acid phosphatase 1 (SAP1) of Leishmania mexicana for optimiz...
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ژورنال
عنوان ژورنال: Microbial Cell Factories
سال: 2012
ISSN: 1475-2859
DOI: 10.1186/1475-2859-11-97